(一)、承擔(dān)的科研項(xiàng)目 (1) 國家自然科學(xué)基金委員會, 面上項(xiàng)目, 31770903, lncRNA介導(dǎo)的ceRNA調(diào)控網(wǎng)絡(luò)在水稻干旱脅迫應(yīng)答中的功能研究, 2018.1-2021.12, 60萬元, 完成, 主持 (2) 國家自然科學(xué)基金委員會, 青年項(xiàng)目, 31400712, 基于microRNA協(xié)同調(diào)控模塊挖掘和驗(yàn)證腎透明細(xì)胞癌聯(lián)合診斷標(biāo)記, 2015.1-2017.12, 24萬元, 完成, 主持 (3) 蘇州市科技計(jì)劃, 農(nóng)業(yè)項(xiàng)目, SNG201905, 氨基酸螯合稀土鑭提高水稻抗逆性能的分子機(jī)制及應(yīng)用研究, 2020.1-2022.12, 5萬元, 在研, 主持 (4) 江蘇省高校自然科學(xué)基金,面上項(xiàng)目,13KJB180021,基于microRNA調(diào)控網(wǎng)絡(luò)的新型前列腺癌診斷標(biāo)記的構(gòu)建,2014.1-2015.12,完成,主持 (5) 蘇州市科技計(jì)劃, 農(nóng)業(yè)項(xiàng)目, SNG201409, 水稻逆境脅迫應(yīng)答microRNA標(biāo)記的篩選及調(diào)控機(jī)制研究, 2014.7-2017.6, 8萬元, 完成, 主持 (二)、獲獎成果 2023年6月,永樂高131net說課競賽,二等獎 2020年9月,永樂高131net優(yōu)秀教學(xué)成果獎,二等獎 2020年7月,全國老員工生命科學(xué)創(chuàng)新創(chuàng)業(yè)大賽,一等獎,指導(dǎo)教師 2019年9月,互聯(lián)網(wǎng)+創(chuàng)新創(chuàng)業(yè)大賽,江蘇省三等獎,指導(dǎo)教師 2018年6月,江蘇省“青藍(lán)工程”優(yōu)秀青年骨干教師 2018年9月,永樂高131net優(yōu)秀教學(xué)成果獎,一等獎 2014年9月,蘇州市自然科學(xué)優(yōu)秀學(xué)術(shù)論文,一等獎 2016年9月,蘇州市優(yōu)秀教育工作者 2008年6月,永樂高131net青年教師講課競賽,一等獎 2018年12月,永樂高131net青年教師講課競賽,一等獎 2013年6月,永樂高131net微課教學(xué)競賽,一等獎 2013年9月,江蘇省微課教學(xué)競賽,三等獎 2014年10月,全國高校微課教學(xué)比賽,二等獎 2014年6月,江蘇省本科高校青年教師講課競賽,二等獎 2014年9月,青年教師標(biāo)兵 2014年9月,交行獎教金 2015年1月,永樂高131net優(yōu)秀青年骨干教師,考核優(yōu)秀 2016年9月,永樂高131net優(yōu)秀教師 2018年1月,永樂高131net優(yōu)青培養(yǎng)對象 2018年9月,蘇州國際教育園,最佳人氣課程獎 |
主要代表性論文: 第一作者: 1. Chen, J, Zhang, Y, Shen, B. Bioinformatics for the Origin and Evolution of Viruses. Adv Exp Med Biol. 2022;1368:53-71. 2. Chen, J., Zhong, Y.,LncRNA TCONS_00021861 is functionally associated with drought tolerance in rice (Oryza sativa) via competing endogenous RNA regulation,BMC Plant Biology,2021.9 3. Chen, J., Zhong, Y., Li, L.:miR?124 and miR?203 synergistically inactivate EMT pathway via coregulation of ZEB2 in clear cell renal cell carcinoma (ccRCC), J Transl Med, 2020, 18, 2020 4. Chen, J., Zhong, Y., Li, L.: Integrative analysis reveals drought-responsive microrna-MRNA regulatory modules in Oryza sativa, Basic & Clinical Pharmacology & Toxicology, 2018, 124(1), 2018 5. Chen, J., Zhong, Y., Li, L.: Multiple Regression Analysis Reveals MicroRNA Regulatory Networks in Oryza sativa under Drought Stress, Int J Genomics, 2018: 9395261, 2018 6. Chen, J., Lin, Y., Shen, B.: Informatics for Precision Medicine and Healthcare. Adv Exp Med Biol, 1005: 1, 2017 7. Chen, J., Miao, Z., Xue, B. et al.: Long Non-coding RNAs in Urologic Malignancies: Functional Roles and Clinical Translation. J Cancer, 7: 1842, 2016 8. Chen, J., Shen, B.: RNA Bioinformatics for Precision Medicine. Adv Exp Med Biol, 939: 21, 2016 9. Chen, J., Sun, M., Shen, B.: Deciphering oncogenic drivers: from single genes to integrated pathways. Brief Bioinform, 2014 10. Chen, J., Qian, F., Yan, W. et al.: Translational biomedical informatics in the cloud: present and future. BioMed Research International, 2013: 658925, 2013 11. Chen, J., Shen, B.: Network Biomarkers for Diagnosis and Prognosis of Human Prostate Cancer. In: Bioinformatics for Diagnosis, Prognosis and Treatment of Complex Diseases: Springer Netherlands, pp. 207-220, 2013 12. Chen, J., Wang, Y., Shen, B. et al.: Molecular signature of cancer at gene level or pathway level? Case studies of colorectal cancer and prostate cancer microarray data. Computational and Mathematical Methods in Medicine, 2013: 909525, 2013 13. Chen, J., Zhang, D., Yan, W. et al.: Translational bioinformatics for diagnostic and prognostic prediction of prostate cancer in the next-generation sequencing era. BioMed Research International, 2013: 901578, 2013 14. Chen, J., Zhang, D., Zhang, W. et al.: Clear cell renal cell carcinoma associated microRNA expression signatures identified by an integrated bioinformatics analysis. Journal of Translational Medicine, 11: 169, 2013 15. Chen, J., Chen, L., Shen, B.: Identification of Network Biomarkers for Cancer Diagnosis. In: Bioinformatics of Human Proteomics. Edited by X. Wang: Springer Netherlands, pp. 257-275, 2012 16. Chen, J., Shen, B.: Computational analysis of amino acid mutation: a proteome wide perspective. Current Proteomics, 6: 228, 2009 17. Chen, J., Wang, Y., Guo, D. et al.: A systems biology perspective on rational design of peptide vaccine against virus infections. Current Topics in Medicinal Chemistry, 12: 1310, 2012 18. Chen, J., Zhang, D., Zhang, W. et al.: An integrative framework for identifying consistent microRNA expression signatures associated with clear cell renal cell carcinoma. Presented at the Systems Biology (ISB), 2012 IEEE 6th International Conference on, Xi'an, China, August 18-20, 2012, 2012 19. Liu, B., Chen, J., Shen, B.: Genome-wide analysis of the transcription factor binding preference of human bi-directional promoters and functional annotation of related gene pairs. BMC Systems Biology, 5: S2, 2011 (共同一作) 通信作者: 1. Zhong, Y., Chen, J.*: Ameliorative effects of Lanthanum(Ⅲ) on Copper(Ⅱ) stressed rice (Oryza sativa) and its molecular mechanism revealed by transcriptome profiling. Plant Physiology and Biochemistry, 2020:152, 2020 2. Gao, Y., Chen, J.*: Informatics for Nutritional Genetics and Genomics. Adv Exp Med Biol, 1005: 143, 2017 3. 20. Shen, Y., Zhang, S., Zhou, J. Chen, J.*: Cohort Research in "Omics" and Preventive Medicine. Adv Exp Med Biol, 1005: 193, 2017 4. Yan, W., Wang, S., Sun, Z., Chen, W., Chen, J.*: Identification of microRNAs as potential biomarker for gastric cancer by system biological analysis. Biomed Res Int, 2014: 901428, 2014 代表性授權(quán)專利: 1. 發(fā)明專利 2021.06授權(quán) 提高砷脅迫水稻耐受性的microRNA基因及其應(yīng)用 發(fā)明專利 201810191587.7第一作者 |